Protein: MYO1
Myosin-1 (Type II myosin)

Gene: MYO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 195
UniProt ID: P08964

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000142 - cellular bud neck contractile ring
GO:0000146 - microfilament motor activity
GO:0000281 - mitotic cytokinesis
GO:0000920 - septum digestion after cytokinesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

477597

MLC1
Myosin light chain 1

7

15

Small-scale

0.962

High

477611

ACT
Actin

4

17

Small-scale

0.909

High

477483

MYO1
Myosin-1

3

18

Small-scale

0.828

High

477511

MYO2
Myosin-2

2

18

High-throughput

0.802

High

477530

MYO4
Myosin-4

2

19

High-throughput

0.802

High

477652

IQG1
Ras GTPase-activating-like protein IQG1

2

11

Small-scale

0.776

High

477641

MLC2
Myosin light chain 2

8

18

Small-scale

0.751

High

477603

BNI5
Bud neck protein 5

3

0

Small-scale

0.619

High

477490

HSP71
Heat shock protein SSA1

2

3

Small-scale

0.614

High

477635

CYK2
Cytokinesis protein 2

2

5

Small-scale

0.595

High

477506

BIP
Endoplasmic reticulum chaperone BiP

2

4

Small-scale

0.586

High

477515

SPA2
Protein SPA2

2

8

Small-scale

0.584

High

477528

SMY1
Kinesin-related protein SMY1

2

8

Small-scale

0.584

High

477509

SEC2
Rab guanine nucleotide exchange factor SEC2

2

0

Small-scale

0.583

High

477533

HSP7F
Heat shock protein homolog SSE1

2

5

Small-scale

0.571

High

477581

TAF1
Transcription initiation factor TFIID subunit 1

2

1

High-throughput

0.567

High

477484

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

Small-scale

0.552

High

477502

HSC82
ATP-dependent molecular chaperone HSC82

1

8

Small-scale

0.552

High

477505

ABP1
Actin-binding protein

1

8

Small-scale

0.552

High

477514

TRX2
Thioredoxin-2

1

2

Small-scale

0.552

High

477557

BZZ1
Protein BZZ1

1

2

Small-scale

0.552

High

477491

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

477542

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.541

High

477512

PWP1
Periodic tryptophan protein 1

1

3

High-throughput

0.536

High

477525

MCM5
Minichromosome maintenance protein 5

1

8

High-throughput

0.536

High

477539

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.536

High

364878

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.529

High

477500

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.529

High

477522

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.529

High

477529

APE2
Aminopeptidase 2, mitochondrial

1

0

Small-scale

0.529

High

477584

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.529

High

477610

DOS2
Protein DOS2

1

0

Small-scale

0.529

High

477510

PDI
Protein disulfide-isomerase

1

2

Small-scale

0.504

High

477609

ERG5
C-22 sterol desaturase ERG5

1

1

High-throughput

0.494

High

477642

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.493

High

477621

GCN5
Histone acetyltransferase GCN5

1

12

High-throughput

0.489

High

477576

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.486

High

477640

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

477543

CASP
Protein CASP

1

19

Small-scale

0.481

High

460294

SYV
Valine--tRNA ligase, mitochondrial

1

2

High-throughput

0.481

High

477486

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

10

Small-scale

0.481

High

477517

KPC1
Protein kinase C-like 1

1

10

High-throughput

0.481

High

477547

DYHC
Dynein heavy chain, cytoplasmic

1

3

High-throughput

0.481

High

477560

END3
Actin cytoskeleton-regulatory complex protein END3

1

2

High-throughput

0.481

High

477572

TBP6
Probable 26S proteasome subunit YTA6

1

4

High-throughput

0.481

High

477590

KEL2
Kelch repeat-containing protein 2

1

12

Small-scale

0.481

High

477613

MDM1
Structural protein MDM1

1

1

High-throughput

0.481

High

477617

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

8

Small-scale

0.481

High

477620

COFI
Cofilin

1

5

Small-scale

0.481

High

477622

VPS60
Vacuolar protein-sorting-associated protein 60

1

7

High-throughput

0.481

High

477628

VPS20
Vacuolar protein sorting-associated protein 20

1

7

High-throughput

0.481

High

477656

SKS1
Serine/threonine-protein kinase SKS1

1

6

High-throughput

0.481

High

477659

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

1

Small-scale

0.481

High

358087

ADH1
Alcohol dehydrogenase 1

1

1

Small-scale

0.479

High

366892

ATPB
ATP synthase subunit beta, mitochondrial

1

5

Small-scale

0.479

High

452783

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

Small-scale

0.479

High

477496

ATC1
Calcium-transporting ATPase 1

1

2

Small-scale

0.479

High

477499

CHS2
Chitin synthase 2

1

1

Small-scale

0.479

High

477504

STI1
Heat shock protein STI1

1

5

Small-scale

0.479

High

477527

HS104
Heat shock protein 104

1

1

Small-scale

0.479

High

477552

GBLP
Small ribosomal subunit protein RACK1

1

7

High-throughput

0.479

High

477555

ECM29
Proteasome component ECM29

1

2

High-throughput

0.479

High

477541

NUF2
Kinetochore protein NUF2

1

4

High-throughput

0.470

High

477612

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

3

High-throughput

0.464

High

477497

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

Small-scale

0.460

High

477518

STE50
Protein STE50

1

0

High-throughput

0.460

High

477526

EF1G1
Elongation factor 1-gamma 1

1

0

Small-scale

0.460

High

477531

SMI1
Cell wall assembly regulator SMI1

1

0

Small-scale

0.460

High

477550

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.460

High

477564

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

477583

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.460

High

477593

PSP1
Protein PSP1

1

0

High-throughput

0.460

High

477594

SHE4
SWI5-dependent HO expression protein 4

1

0

Small-scale

0.460

High

477607

AF9
Protein AF-9 homolog

1

0

High-throughput

0.460

High

477625

VPS64
Vacuolar protein sorting-associated protein 64

1

0

High-throughput

0.460

High

477644

WHI4
Protein WHI4

1

0

Small-scale

0.460

High

477654

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

434706

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435677

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

477489

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

477492

METK1
S-adenosylmethionine synthase 1

1

0

Small-scale

0.458

High

477493

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.458

High

477498

RL30
Large ribosomal subunit protein eL30

1

0

Small-scale

0.458

High

477503

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

0

Small-scale

0.458

High

477508

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

Small-scale

0.458

High

477532

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

Small-scale

0.458

High

477535

DRS1
ATP-dependent RNA helicase DRS1

1

0

Small-scale

0.458

High

477537

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

477553

OLA1
Obg-like ATPase 1

1

0

Small-scale

0.458

High

477554

ENP1
Essential nuclear protein 1

1

0

Small-scale

0.458

High

477570

RGI2
Respiratory growth induced protein 2

1

0

Small-scale

0.458

High

477589

RS12
Small ribosomal subunit protein eS12

1

0

Small-scale

0.458

High

477605

INN1
Ingression protein 1

1

0

Small-scale

0.458

High

477606

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.458

High

477638

YL287
Uncharacterized protein YLR287C

1

0

Small-scale

0.458

High

477639

RGC1
Regulator of the glycerol channel 1

1

0

Small-scale

0.458

High

477643

CYK3
Cytokinesis protein 3

1

0

Small-scale

0.458

High

477646

BMS1
Ribosome biogenesis protein BMS1

1

0

Small-scale

0.458

High

477651

NCE2
Non-classical export protein 2

1

0

Small-scale

0.458

High

392044

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

477495

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

477501

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

477534

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.445

High

477561

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.445

High

477563

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

477568

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

431968

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.439

High

477507

TUP1
General transcriptional corepressor TUP1

1

7

High-throughput

0.439

High

477545

BDF1
Bromodomain-containing factor 1

1

11

High-throughput

0.439

High

477566

TSC11
Target of rapamycin complex 2 subunit TSC11

1

3

High-throughput

0.439

High

477571

NACB2
Nascent polypeptide-associated complex subunit beta-2

1

8

High-throughput

0.439

High

477616

MLP1
Protein MLP1

1

18

Small-scale

0.439

High

477637

ENT2
Epsin-2

1

4

High-throughput

0.439

High

477647

MMT2
Mitochondrial metal transporter 2

1

1

Small-scale

0.439

High

368553

PMG1
Phosphoglycerate mutase 1

1

1

Small-scale

0.437

High

419324

H2A1
Histone H2A.1

1

2

Small-scale

0.437

High

434480

RL22A
Large ribosomal subunit protein eL22A

1

2

Small-scale

0.437

High

477485

RL31A
Large ribosomal subunit protein eL31A

1

1

Small-scale

0.437

High

477488

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

477494

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

Small-scale

0.437

High

477516

RS3A2
Small ribosomal subunit protein eS1B

1

2

Small-scale

0.437

High

477520

SRO9
RNA-binding protein SRO9

1

3

Small-scale

0.437

High

477524

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

477540

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

477546

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

477580

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

Small-scale

0.437

High

477599

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

477602

NOP13
Nucleolar protein 13

1

2

Small-scale

0.437

High

477634

RRP5
rRNA biogenesis protein RRP5

1

1

Small-scale

0.437

High

477645

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

477519

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

477582

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

477588

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

477595

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

477604

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

477633

DYN3
Cytoplasmic dynein intermediate light chain DYN3

1

0

High-throughput

0.426

High

477653

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

477544

SPT7
SAGA complex subunit SPT7

1

7

High-throughput

0.407

High

477591

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

7

High-throughput

0.407

High

456480

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

2

0

High-throughput

0.313

High

477596

ALAT1
Alanine aminotransferase, mitochondrial

1

0

Small-scale

0.288

High

477636

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

Small-scale

0.288

High

477624

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.279

Low

477579

MIL1
Probable lipase MIL1

1

0

High-throughput

0.269

Low

427017

FUR4
Uracil permease

1

0

Small-scale

0.251

Low

477513

DAL82
Protein DAL82

1

0

Small-scale

0.251

Low

477538

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

477548

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

477551

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low

477562

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.251

Low

477567

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.251

Low

477569

YNU8
Uncharacterized protein YNL208W

1

0

Small-scale

0.251

Low

477573

NOP2
25S rRNA

1

0

High-throughput

0.251

Low

477574

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.251

Low

477575

UFE1
Syntaxin UFE1

1

0

High-throughput

0.251

Low

477578

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

477586

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.251

Low

477587

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

477601

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.251

Low

477618

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

477619

SLU7
Pre-mRNA-splicing factor SLU7

1

0

Small-scale

0.251

Low

477626

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.251

Low

477627

LRS4
Monopolin complex subunit LRS4

1

0

High-throughput

0.251

Low

477629

EMI1
Early meiotic induction protein 1

1

0

Small-scale

0.251

Low

477630

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

477648

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

0

High-throughput

0.251

Low

477655

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

477658

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.251

Low

383425

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

434115

RL36A
Large ribosomal subunit protein eL36A

1

0

Small-scale

0.249

Low

454779

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

477487

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

477521

KRR1
KRR1 small subunit processome component

1

0

Small-scale

0.249

Low

477523

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

477536

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

477549

MUD2
Splicing factor MUD2

1

0

Small-scale

0.249

Low

477556

CIC1
Proteasome-interacting protein CIC1

1

0

Small-scale

0.249

Low

477558

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

477565

NUG1
Nuclear GTP-binding protein NUG1

1

0

Small-scale

0.249

Low

477577

KRI1
Protein KRI1

1

0

Small-scale

0.249

Low

477585

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

477600

YG5X
Putative methyltransferase YGR283C

1

0

Small-scale

0.249

Low

477608

YNF0
Uncharacterized protein YNL050C

1

0

Small-scale

0.249

Low

477614

RL6A
Large ribosomal subunit protein eL6A

1

0

Small-scale

0.249

Low

477623

TMA23
Protein TMA23

1

0

Small-scale

0.249

Low

477631

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

477632

RTN1
Reticulon-like protein 1

1

0

Small-scale

0.249

Low

477649

SAS10
Something about silencing protein 10

1

0

Small-scale

0.249

Low

477650

MAK21
Ribosome biogenesis protein MAK21

1

0

Small-scale

0.249

Low

477657

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.249

Low

477559

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

477592

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.232

Low

477598

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.232

Low

477615

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025