Interactor 1: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: PLCG1 (Q62077)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 15953601, 22561606
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2, SH2~SH2, SH2~SH3_1, PH~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005168 - neurotrophin TRKA receptor binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 217
Mm

1 1302
+ Rn
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024