HitPredict

Interactor 1: CSK21 (Q60737)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: Csnk2a1

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	21589869, 23892456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 391 Mm			1 305
+	Hs
		934485 CSK21_HUMAN (1-391): 1.21e-135: 394: 98.72		NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72
+	Hs
		620139 CSK21_HUMAN (1-391): 1.21e-135: 394: 98.72		PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81
+	Hs
		679087 CSK21_HUMAN (1-391): 1.21e-135: 394: 98.72		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		641368 CSK21_HUMAN (1-391): 1.21e-135: 394: 98.72		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Dm
		437104 CSK2A_DROME (5-338): 3.08e-130: 378: 86.83		Q9W1H7_DROME (37-182): 1.44e-33: 124: 19.61
+	Dm
		283684 CSK2A_DROME (5-338): 3.08e-130: 378: 86.83		O76136_DROME (81-156): 2.17e-34: 122: 26.32
+	Hs
		586585 CSK22_HUMAN (1-334): 1.9e-119: 352: 85.08		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		686552 CDK3_HUMAN (36-331): 1.04e-120: 353: 31.27		OTX2_HUMAN (61-282): 1.61e-32: 123: 18.86
+	Hs
		641372 CDK3_HUMAN (36-331): 1.04e-120: 353: 31.27		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		213296 CSK22_HUMAN (1-334): 1.9e-119: 352: 85.08		TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39
+	Hs
		211795 CSK22_HUMAN (1-334): 1.9e-119: 352: 85.08		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08