HitPredict

Interactor 1: KHDR1 (Q60749)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: Khdrbs1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0035591 - signaling adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Mm			1 377
+	Hs
		557667 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		NCK1_HUMAN (1-377): 2.9e-97: 295: 98.94
+	Hs
		209037 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		NCK2_HUMAN (1-376): 7.37e-90: 277: 68.50
+	Rn
		1144374 KHDR1_RAT (1-443): 0: 522: 98.87		P85A_RAT (102-376): 4.66e-22: 99.8: 15.88
+	Mm
		763394 KHDR1_MOUSE (1-443): 0: 522: 100.00		FYN_MOUSE (6-130): 3.25e-22: 99.8: 21.26
+	Mm
		980964 KHDR1_MOUSE (1-443): 0: 522: 100.00		YES_MOUSE (5-130): 7.92e-22: 98.7: 20.31
+	Mm
		403437 KHDR1_MOUSE (1-443): 0: 522: 100.00		SRC_MOUSE (6-130): 5.82e-19: 90.1: 21.26
+	Mm
		1141126 KHDR1_MOUSE (1-443): 0: 522: 100.00		GRB2_MOUSE (3-58): 7.7e-17: 80.6: 28.57
+	Hs
		433330 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		YES_HUMAN (6-152): 2.64e-22: 100: 19.87
+	Hs
		655330 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		P85A_HUMAN (241-376): 2.35e-22: 100: 19.57
+	Hs
		412149 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		FYN_HUMAN (6-130): 3.47e-22: 99.8: 21.26
+	Hs
		454827 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		FGR_HUMAN (6-130): 3.16e-22: 99.8: 21.26
+	Hs
		442815 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		HCK_HUMAN (2-130): 1.23e-21: 98.3: 22.31
+	Hs
		789110 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		FRK_HUMAN (3-150): 3.51e-19: 91: 17.20
+	Hs
		522933 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		SRC_HUMAN (6-130): 5.78e-19: 90.1: 21.26
+	Hs
		782780 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		CSK_HUMAN (4-143): 8.06e-17: 83.7: 14.38
+	Hs
		924509 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		GRB2_HUMAN (3-58): 7.33e-17: 80.6: 28.57
+	Hs
		991778 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		ITSN1_HUMAN (1-127): 4.93e-15: 78.8: 15.75
+	Hs
		991842 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		SH3K1_HUMAN (6-79): 2.48e-14: 76.2: 19.74
+	Hs
		991902 KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36		ITSN2_HUMAN (7-62): 2.96e-12: 70.2: 30.36
+	Mm
		763412 KHDR2_MOUSE (100-443): 2.67e-128: 376: 60.23		FYN_MOUSE (6-130): 3.25e-22: 99.8: 21.26