HitPredict

Interactor 1: TSH3 (Q63HK5)
Teashirt homolog 3 (Zinc finger protein 537)
Gene: TSHZ3

Interactor 2: KLF15 (Q9UIH9)
Krueppel-like factor 15 (Kidney-enriched krueppel-like factor)
Gene: KLF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1081 Hs			1 416
+	Hs
		884181 TSH3_HUMAN (1-1081): 0: 1011: 100.00		KLF3_HUMAN (319-403): 1.71e-29: 119: 63.53
+	Hs
		1046699 NIPBL_HUMAN (413-892): 3.49e-27: 122: 11.31		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		1046715 KMT2C_HUMAN (456-942): 7.72e-27: 121: 11.18		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		316915 NIPBL_HUMAN (413-892): 3.49e-27: 122: 11.31		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		1154070 NIPBL_HUMAN (413-892): 3.49e-27: 122: 11.31		KLF16_HUMAN (319-403): 9.02e-31: 120: 62.35
+	Hs
		884184 NIPBL_HUMAN (413-892): 3.49e-27: 122: 11.31		KLF3_HUMAN (319-403): 1.71e-29: 119: 63.53
+	Hs
		1154084 NIPBL_HUMAN (413-892): 3.49e-27: 122: 11.31		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		1243850 KMT2C_HUMAN (456-942): 7.72e-27: 121: 11.18		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		152643 KMT2D_HUMAN (421-930): 2.72e-10: 67.1: 9.96		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		152569 KMT2D_HUMAN (421-930): 2.72e-10: 67.1: 9.96		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		435145 TITIN_HUMAN (492-941): 5.51e-10: 66.3: 8.49		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		152686 KMT2D_HUMAN (421-930): 2.72e-10: 67.1: 9.96		KLF16_HUMAN (319-403): 9.02e-31: 120: 62.35
+	Hs
		152621 KMT2D_HUMAN (421-930): 2.72e-10: 67.1: 9.96		KLF3_HUMAN (319-403): 1.71e-29: 119: 63.53
+	Hs
		152697 KMT2D_HUMAN (421-930): 2.72e-10: 67.1: 9.96		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		1056958 MDC1_HUMAN (414-919): 2.78e-12: 73.5: 12.55		ZN251_HUMAN (44-248): 1.85e-10: 64.7: 9.72