HitPredict

Interactor 1: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Interactor 2: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.605

Property	Details
Experiments	8858149, 24981171
Identification Methods	two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000710 - meiotic mismatch repair GO:0005634 - nucleus GO:0006298 - mismatch repair
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 258 Sc			1 769
+	Hs
		517112 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		MLH1_HUMAN (1-769): 0: 840: 36.41
+	Hs
		517150 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		PMS2_HUMAN (2-502): 2.3e-147: 454: 22.64
+	Hs
		517526 PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52		MLH3_HUMAN (5-467): 5.97e-109: 364: 19.92
+	Sc
		536211 PCNA_YEAST (1-258): 5.31e-95: 281: 100.00		PMS1_YEAST (4-508): 5.46e-125: 396: 23.21
+	Sc
		550582 PCNA_YEAST (1-258): 5.31e-95: 281: 100.00		MLH3_YEAST (1-420): 3.7e-104: 337: 19.45