HitPredict

Interactor 1: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Interactor 2: LMO3 (Q8TAP4)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)
Gene: LMO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 851 Hs			1 145
+	Hs
		638310 KANK2_HUMAN (1-851): 0: 559: 100.00		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		903734 KANK2_HUMAN (1-851): 0: 559: 100.00		LMO4_HUMAN (11-142): 3.16e-41: 136: 50.76
+	Hs
		638513 KANK2_HUMAN (1-851): 0: 559: 100.00		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		823419 KANK2_HUMAN (1-851): 0: 559: 100.00		PAXI_HUMAN (3-135): 2.8e-32: 121: 24.06
+	Hs
		1144790 KANK2_HUMAN (1-851): 0: 559: 100.00		PDLI7_HUMAN (70-145): 5.47e-15: 72.3: 23.68
+	Hs
		1144801 KANK2_HUMAN (1-851): 0: 559: 100.00		LHX3_HUMAN (4-68): 2.41e-11: 61.9: 21.21
+	Hs
		822638 KANK2_HUMAN (1-851): 0: 559: 100.00		LHX1_HUMAN (4-67): 3.28e-11: 61.5: 26.15
+	Hs
		903713 ASPP2_HUMAN (48-840): 1.69e-69: 251: 15.57		LMO4_HUMAN (11-142): 3.16e-41: 136: 50.76
+	Hs
		1281184 EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00		LHX4_HUMAN (72-144): 4.55e-12: 63.8: 19.18
+	Hs
		1334137 EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00		LHX3_HUMAN (4-68): 2.41e-11: 61.9: 21.21
+	Hs
		822681 EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00		LHX1_HUMAN (4-67): 3.28e-11: 61.5: 26.15
+	Hs
		839827 EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00		LHX2_HUMAN (12-78): 7.86e-10: 57.7: 23.53
+	Hs
		823450 ANR52_HUMAN (181-793): 1.55e-50: 194: 13.17		PAXI_HUMAN (3-135): 2.8e-32: 121: 24.06
+	Hs
		1043721 ASPP2_HUMAN (48-840): 1.69e-69: 251: 15.57		LHX4_HUMAN (72-144): 4.55e-12: 63.8: 19.18
+	Hs
		1167334 BCOR_HUMAN (137-843): 3.57e-60: 225: 15.89		LHX3_HUMAN (4-68): 2.41e-11: 61.9: 21.21
+	Hs
		839767 BCOR_HUMAN (137-843): 3.57e-60: 225: 15.89		LHX2_HUMAN (12-78): 7.86e-10: 57.7: 23.53
+	Hs
		638375 EHMT2_HUMAN (5-742): 2.01e-21: 102: 10.40		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		1219793 ANKH1_HUMAN (349-849): 1.99e-26: 119: 13.92		LMO3_HUMAN (1-145): 3.61e-37: 125: 100.00
+	Hs
		823441 ANKH1_HUMAN (349-849): 1.99e-26: 119: 13.92		PAXI_HUMAN (3-135): 2.8e-32: 121: 24.06
+	Hs
		257707 ANR17_HUMAN (553-836): 3.23e-37: 154: 20.42		LHX9_HUMAN (77-143): 1.21e-10: 60: 25.00