HitPredict

Interactor 1: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: MLP3B (Q9CQV6)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: Map1lc3b

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31286822, 18083104
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005776 - autophagosome GO:0005829 - cytosol GO:0006914 - autophagy GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0044754 - autolysosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 442 Mm			1 125
+	Mm
		1145358 SQSTM_MOUSE (1-442): 0: 777: 100.00		MLP3A_MOUSE (1-120): 1e-54: 168: 82.50
+	Hs
		1036882 SQSTM_HUMAN (1-442): 0: 715: 89.82		MLP3B_HUMAN (1-125): 1.94e-55: 170: 95.20
+	Hs
		1036900 SQSTM_HUMAN (1-442): 0: 715: 89.82		MLP3A_HUMAN (1-120): 1e-54: 168: 82.50
+	Hs
		61895 SQSTM_HUMAN (1-442): 0: 715: 89.82		MP3B2_HUMAN (1-125): 1.15e-54: 168: 94.40
+	Hs
		891130 SQSTM_HUMAN (1-442): 0: 715: 89.82		GBRL2_HUMAN (7-120): 1.84e-53: 165: 39.47
+	Hs
		1036661 SQSTM_HUMAN (1-442): 0: 715: 89.82		Q6IAW1_HUMAN (7-120): 1.18e-52: 163: 31.58
+	Hs
		306157 SQSTM_HUMAN (1-442): 0: 715: 89.82		GBRAP_HUMAN (7-120): 1.18e-52: 163: 31.58
+	Hs
		1036868 SQSTM_HUMAN (1-442): 0: 715: 89.82		MLP3C_HUMAN (1-120): 3.93e-51: 160: 55.00
+	Hs
		1036891 SQSTM_HUMAN (1-442): 0: 715: 89.82		GBRL1_HUMAN (7-120): 1.05e-51: 160: 32.46
+	Ce
		94010 F1LIM5_CAEEL (79-230): 3.33e-44: 164: 23.98		LGG1_CAEEL (6-120): 2.63e-51: 160: 33.04
+	Ce
		94015 F1LIM5_CAEEL (79-230): 3.33e-44: 164: 23.98		LGG2_CAEEL (6-120): 1.05e-44: 143: 59.13
+	Hs
		306226 MIB1_HUMAN (105-228): 1.65e-27: 117: 27.69		GBRAP_HUMAN (7-120): 1.18e-52: 163: 31.58
+	Dm
		536028 REF2P_DROME (112-173): 2.24e-18: 89.4: 41.27		Q9W2S2_DROME (7-122): 3.16e-54: 167: 31.03
+	Hs
		320003 HERC2_HUMAN (120-197): 1.35e-11: 69: 32.50		MLP3B_HUMAN (1-125): 1.94e-55: 170: 95.20