HitPredict

Interactor 1: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: TRIB3 (Q8K4K2)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)
Gene: TRIB3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31286822
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 442 Mm			1 354
+	Hs
		1036829 SQSTM_HUMAN (1-442): 0: 715: 89.82		TRIB3_HUMAN (1-354): 1.2e-140: 404: 73.18
+	Hs
		1036686 SQSTM_HUMAN (1-442): 0: 715: 89.82		MARK2_HUMAN (13-353): 2.51e-128: 387: 21.57
+	Hs
		568653 SQSTM_HUMAN (1-442): 0: 715: 89.82		KAPCA_HUMAN (28-346): 9.2e-130: 376: 18.29
+	Hs
		1036549 SQSTM_HUMAN (1-442): 0: 715: 89.82		KCC2D_HUMAN (60-317): 1.88e-111: 335: 26.18
+	Hs
		319892 HERC2_HUMAN (120-197): 1.35e-11: 69: 32.50		MARK2_HUMAN (13-353): 2.51e-128: 387: 21.57