Interactor 1: ERBB4 (Q15303)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4
Interactor 2: TAB1 (Q15750)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)
Gene: TAB1
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 0.60 | 0.541 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28065597 |
| Identification Methods | two hybrid, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0007165 - signal transduction GO:0043410 - positive regulation of MAPK cascade |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
