HitPredict

Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: FBN2 (P35556)
Fibrillin-2 [Cleaved into: Placensin]
Gene: FBN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	25034023
Identification Methods	solid phase assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EGF_3~fn3, EGF_CA~fn3
Common GO terms	GO:0005201 - extracellular matrix structural constituent GO:0005576 - extracellular region GO:0031012 - extracellular matrix GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2477 Hs			1 2912
+	Hs
		363214 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBN3_HUMAN (1-1624): 8.23e-112: 403: 24.14
+	Hs
		362881 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBN1_HUMAN (1742-2819): 1.44e-54: 214: 21.20
+	Hs
		363151 FINC_HUMAN (1-2477): 0: 1538: 100.00		LTBP1_HUMAN (1-812): 7.93e-29: 129: 16.35
+	Hs
		362826 FINC_HUMAN (1-2477): 0: 1538: 100.00		TENA_HUMAN (2-239): 3.7e-23: 111: 17.77
+	Hs
		363076 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBLN2_HUMAN (93-427): 2.59e-20: 101: 24.48
+	Hs
		362819 FINC_HUMAN (1-2477): 0: 1538: 100.00		FBLN1_HUMAN (248-360): 4.28e-10: 67.4: 40.87
+	Hs
		957542 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		LTBP2_HUMAN (2144-2816): 9.22e-30: 132: 21.62
+	Hs
		439247 MMP2_HUMAN (342-404): 1.25e-15: 85.1: 55.56		SCUB3_HUMAN (1483-1838): 2.64e-15: 84.7: 27.18
+	Hs
		957263 PGBM_HUMAN (122-745): 3.46e-09: 65.1: 9.56		FBLN2_HUMAN (93-427): 2.59e-20: 101: 24.48
+	Hs
		540435 MMP9_HUMAN (301-404): 2.05e-14: 81.3: 42.31		SCUB3_HUMAN (1483-1838): 2.64e-15: 84.7: 27.18