HitPredict

Interactor 1: RNF43 (Q68DV7)
E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43)
Gene: RNF43

Interactor 2: UBXN4 (Q92575)
UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)
Gene: UBXN4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34702444
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 508
+	Hs
		1148271 RNF43_HUMAN (1-783): 0: 711: 100.00		FAF1_HUMAN (171-397): 3.41e-47: 175: 19.38
+	Hs
		979314 RNF43_HUMAN (1-783): 0: 711: 100.00		UBXN1_HUMAN (85-396): 4.2e-44: 159: 22.64
+	Hs
		1204802 GOLI_HUMAN (28-381): 3.32e-78: 259: 18.45		UBXN4_HUMAN (1-508): 1.33e-160: 467: 100.00
+	Hs
		1198639 SYVN1_HUMAN (186-595): 1.11e-42: 166: 15.57		UBXN4_HUMAN (1-508): 1.33e-160: 467: 100.00
+	Hs
		1267628 AMFR_HUMAN (185-512): 5.48e-35: 143: 13.87		UBXN4_HUMAN (1-508): 1.33e-160: 467: 100.00
+	Hs
		1240714 RN149_HUMAN (36-348): 6.63e-79: 261: 17.59		FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18
+	Hs
		1204809 GOLI_HUMAN (28-381): 3.32e-78: 259: 18.45		FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18
+	Hs
		299488 AMFR_HUMAN (185-512): 5.48e-35: 143: 13.87		UBXN7_HUMAN (2-397): 7.46e-87: 277: 15.33
+	Hs
		1198646 SYVN1_HUMAN (186-595): 1.11e-42: 166: 15.57		FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18
+	Mm
		1265759 AMFR_MOUSE (185-538): 2.22e-38: 154: 14.43		UBXN1_MOUSE (85-396): 5.82e-46: 164: 22.96
+	Hs
		1356612 AMFR_HUMAN (185-512): 5.48e-35: 143: 13.87		FAF1_HUMAN (171-397): 3.41e-47: 175: 19.38
+	Hs
		1287221 AMFR_HUMAN (185-512): 5.48e-35: 143: 13.87		FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18
+	Hs
		979373 AMFR_HUMAN (185-512): 5.48e-35: 143: 13.87		UBXN1_HUMAN (85-396): 4.2e-44: 159: 22.64
+	Hs
		116689 SYVN1_HUMAN (186-595): 1.11e-42: 166: 15.57		UBXN8_HUMAN (203-398): 1.28e-35: 135: 15.82