HitPredict

Interactor 1: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 881 Hs			1 1190
+	Hs
		1133715 RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		1345231 RHG35_HUMAN (79-472): 1.53e-65: 241: 20.10		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		1219682 RHG12_HUMAN (53-427): 1.04e-63: 232: 17.90		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		506670 BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		1148376 RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Hs
		1148381 RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Hs
		1232139 RHG18_HUMAN (52-452): 3.53e-65: 233: 17.16		PALS2_HUMAN (423-890): 8.19e-96: 318: 15.77
+	Mm
		1131438 ABR_MOUSE (1-412): 1.2e-70: 252: 18.94		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143388 RHG32_MOUSE (250-462): 2.1e-17: 89.7: 29.41		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89