HitPredict

Interactor 1: MSX1 (P28360)
Homeobox protein MSX-1 (Homeobox protein Hox-7) (Msh homeobox 1-like protein)
Gene: MSX1

Interactor 2: MSX2 (P35548)
Homeobox protein MSX-2 (Homeobox protein Hox-8)
Gene: MSX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 9111364
Identification Methods pull down, two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 22 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 303
Hs

1 267
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+ Mm
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+ Ce
+ Mm
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+ Hs
+ Mm
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+ Mm
+ Mm
+ Dm
+ Ce

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Last updated: 15 Jul 2024