HitPredict

Interactor 1: GIT1 (Q68FF6)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)
Gene: GIT1

Interactor 2: ANS1B (Q8BIZ1)
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)
Gene: Anks1b

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	31388001
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~GIT_SHD
Common GO terms	GO:0005829 - cytosol GO:0014069 - postsynaptic density GO:0048013 - ephrin receptor signaling pathway GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 770 Mm			1 1259
+	Mm
		1206695 ASAP1_MOUSE (2-652): 1.67e-60: 223: 15.32		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Mm
		1112613 AGAP2_MOUSE (2-224): 1.16e-46: 181: 29.15		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Mm
		970499 ANK1_MOUSE (126-595): 7.48e-37: 151: 12.58		ANS1B_MOUSE (1-1259): 0: 938: 100.00
+	Hs
		167036 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANR50_HUMAN (2-859): 6.31e-88: 315: 16.63
+	Mm
		103599 AGAP2_MOUSE (2-224): 1.16e-46: 181: 29.15		ANK3_MOUSE (8-1075): 2.51e-70: 262: 12.20
+	Mm
		103591 ANK3_MOUSE (60-565): 6.42e-37: 152: 12.73		ANK3_MOUSE (8-1075): 2.51e-70: 262: 12.20
+	Hs
		166849 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANR28_HUMAN (2-500): 1.11e-71: 262: 17.60
+	Hs
		167014 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		TNKS2_HUMAN (2-490): 1.86e-64: 241: 16.22
+	Hs
		166869 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		TNKS1_HUMAN (2-570): 8.9e-62: 234: 15.41
+	Hs
		166919 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANK3_HUMAN (5-322): 1.58e-61: 234: 21.75
+	Hs
		166969 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANR44_HUMAN (3-258): 1.64e-59: 225: 24.91
+	Hs
		1335969 AGAP1_HUMAN (2-236): 4.18e-55: 205: 31.93		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41
+	Hs
		1299062 AGAP3_HUMAN (2-224): 1.24e-52: 198: 33.63		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41
+	Hs
		1126898 AN36B_HUMAN (114-766): 1.92e-50: 193: 12.13		AN36C_HUMAN (3-150): 1.44e-15: 84.6: 19.60
+	Hs
		883496 ANK3_HUMAN (174-528): 8.05e-33: 139: 10.36		RIPK4_HUMAN (4-138): 1.7e-27: 122: 23.29
+	Mm
		1112622 AGAP2_MOUSE (2-224): 1.16e-46: 181: 29.15		ANK2_MOUSE (66-258): 3.34e-10: 67: 30.05
+	Mm
		103608 ANK3_MOUSE (60-565): 6.42e-37: 152: 12.73		ANK2_MOUSE (66-258): 3.34e-10: 67: 30.05
+	Hs
		166913 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANK2_HUMAN (66-258): 2.94e-10: 67.4: 30.05
+	Hs
		166971 ANR28_HUMAN (54-365): 8.87e-34: 141: 16.31		ANR52_HUMAN (44-283): 2.18e-10: 67.4: 27.24