Interactor 1: S6A19 (Q695T7)
Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1)
Gene: SLC6A19

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.907

The method score is based on:

Property Details
Experiments 32132184, 888800000006, 36057605, 34189428
Identification Methods x-ray crystallography, pull down, biochemical, affinity chromatography technology, molecular sieving, 3D electron microscopy, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Collectrin~SNF
Common GO terms GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0019058 - viral life cycle
GO:0031526 - brush border membrane
GO:0070062 - extracellular exosome
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 634
Hs

1 805
+ Hs
+ Mm
+ Mm
+ Dm
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024