HitPredict

Interactor 1: A0A024R161 (A0A024R161)
Guanine nucleotide-binding protein subunit gamma
Gene: DNAJC25-GNG10

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 153 Hs			1 1382
+	Hs
		411493 DJC25_HUMAN (1-122): 4.86e-41: 142: 91.80		INSR_HUMAN (1-1382): 0: 1530: 100.00
+	Hs
		411469 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		INSR_HUMAN (1-1382): 0: 1530: 100.00
+	Hs
		411515 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		INSR_HUMAN (1-1382): 0: 1530: 100.00
+	Hs
		435729 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Hs
		435780 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Hs
		435790 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Hs
		383619 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		383929 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		384003 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		384016 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Mm
		1142038 DNJA3_MOUSE (9-141): 3.26e-38: 137: 25.55		MUSK_MOUSE (1017-1291): 3.2e-70: 256: 42.56
+	Hs
		1348102 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53
+	Hs
		666634 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		LTK_HUMAN (1013-1291): 2e-71: 259: 44.52
+	Hs
		169212 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		MUSK_HUMAN (1017-1291): 1.24e-69: 254: 42.22
+	Hs
		385330 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		385615 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		385658 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		1081563 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43
+	Hs
		1081626 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43
+	Hs
		609471 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		FGFR3_HUMAN (1015-1287): 2.21e-62: 231: 40.78