HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1 (Filamin mechanobinding actin cross-linking protein) (Fimbacin)
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005874 - microtubule GO:0036064 - ciliary basal body GO:0051233 - spindle midzone
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 1076
+	Hs
		1290004 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		LUZP1_HUMAN (1-1076): 8.14e-177: 547: 100.00
+	Hs
		587675 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		DESP_HUMAN (44-616): 3.94e-15: 82.9: 10.48
+	Hs
		1143128 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		PLEC_HUMAN (35-503): 1.33e-11: 71.4: 16.50
+	Hs
		1152080 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Hs
		270858 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		ROCK2_HUMAN (1-355): 7.29e-16: 85.2: 13.51
+	Hs
		1281012 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		FLIP1_HUMAN (76-616): 1.65e-13: 77.5: 12.84
+	Hs
		1191504 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82