HitPredict

Interactor 1: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 608 Hs			1 327
+	Hs
		1120774 KLH12_HUMAN (19-575): 8.8e-171: 499: 32.32		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1184998 KLHL8_HUMAN (5-574): 1.07e-158: 470: 28.37		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1184999 KLHL9_HUMAN (387-607): 1.86e-54: 197: 22.81		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1185001 KLH13_HUMAN (387-607): 5.12e-53: 194: 21.93		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		299521 KLH18_HUMAN (461-608): 2.26e-35: 142: 27.33		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1185018 KLH20_HUMAN (269-432): 1.73e-31: 131: 27.44		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1121474 KLH26_HUMAN (365-606): 3.77e-26: 115: 13.53		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1164611 KLH24_HUMAN (448-607): 1.58e-21: 100: 18.56		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		1184911 KLH23_HUMAN (341-574): 5.65e-17: 86.3: 29.63		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00