HitPredict

Interactor 1: NEDD8 (Q15843)
Ubiquitin-like protein NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8)
Gene: NEDD8

Interactor 2: KLDC2 (Q9Y2U9)
Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1)
Gene: KLHDC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36805027
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 406
+	Dm
		57922 RS27A_DROME (1-77): 3.4e-36: 121: 57.14		KLD10_DROME (29-379): 1.62e-64: 218: 21.20
+	Hs
		1154916 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		KLDC3_HUMAN (5-198): 5.29e-29: 118: 16.84
+	Hs
		1154842 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		KLH12_HUMAN (6-156): 1.13e-24: 107: 16.56
+	Hs
		1154945 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		KLHL9_HUMAN (265-402): 1.9e-12: 70.9: 15.75
+	Hs
		1154852 NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00		KLD10_HUMAN (263-399): 1.35e-11: 67.8: 16.89