Protein: KLD10
Kelch domain-containing protein 10

Gene: KLD10, KLHDC10
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q6PID8

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0032874 - positive regulation of stress-activated MAPK cascade

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1154852

NEDD8
Ubiquitin-like protein NEDD8

1

5

High-throughput

0.691

High

1112883

CUL2
Cullin-2

3

20

High-throughput

0.675

High

563934

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.643

High

639345

SCF
Kit ligand

3

0

High-throughput

0.638

High

1104598

IKZF1
DNA-binding protein Ikaros

2

1

High-throughput

0.628

High

1244735

GLMN
Glomulin

2

3

High-throughput

0.628

High

1147182

ELOB
Elongin-B

1

4

High-throughput

0.618

High

1244728

NUDC3
NudC domain-containing protein 3

2

20

High-throughput

0.611

High

733950

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

3

1

High-throughput

0.609

High

1244723

KLD10
Kelch domain-containing protein 10

1

19

High-throughput

0.575

High

1199910

P5CR3
Pyrroline-5-carboxylate reductase 3

2

1

High-throughput

0.549

High

839162

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

4

High-throughput

0.536

High

983847

RBX1
E3 ubiquitin-protein ligase RBX1

1

9

High-throughput

0.536

High

1244733

RIN3
Ras and Rab interactor 3

1

9

High-throughput

0.536

High

1244736

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.536

High

1244740

DCNL1
DCN1-like protein 1

1

8

High-throughput

0.536

High

1244741

TREF1
Transcriptional-regulating factor 1

1

5

High-throughput

0.536

High

1244747

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

1244732

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

0

High-throughput

0.513

High

190399

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.489

High

281348

GGYF1
GRB10-interacting GYF protein 1

1

6

High-throughput

0.489

High

1143059

KPCD1
Serine/threonine-protein kinase D1

1

7

High-throughput

0.489

High

1244724

POTEG
POTE ankyrin domain family member G

1

3

High-throughput

0.489

High

1244725

CERS6
Ceramide synthase 6

1

1

High-throughput

0.489

High

1244726

TBCD9
TBC1 domain family member 9

1

1

High-throughput

0.489

High

1244731

ZN444
Zinc finger protein 444

1

6

High-throughput

0.489

High

1244737

NACC2
Nucleus accumbens-associated protein 2

1

17

High-throughput

0.489

High

1244739

HVCN1
Voltage-gated hydrogen channel 1

1

3

High-throughput

0.489

High

1244743

SCRT1
Transcriptional repressor scratch 1

1

2

High-throughput

0.489

High

1244744

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

6

High-throughput

0.489

High

320699

UBXN7
UBX domain-containing protein 7

1

6

High-throughput

0.479

High

372337

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

406295

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

957420

UBC12
NEDD8-conjugating enzyme Ubc12

1

18

High-throughput

0.479

High

1023249

RBM3
RNA-binding protein 3

1

4

Small-scale

0.479

High

1125132

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

10

High-throughput

0.479

High

1158386

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.479

High

1241656

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

1244738

OPTN
Optineurin

1

15

High-throughput

0.479

High

1244745

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

1244746

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

12

Small-scale

0.479

High

1244749

SHLB1
Endophilin-B1

1

1

High-throughput

0.479

High

1244750

ARI1
E3 ubiquitin-protein ligase ARIH1

1

13

High-throughput

0.479

High

1244727

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.437

High

1244730

MILK2
MICAL-like protein 2

1

1

High-throughput

0.437

High

1030789

DEF5
Defensin alpha 5

2

0

High-throughput

0.328

High

1063918

LOXL1
Lysyl oxidase homolog 1

1

0

High-throughput

0.279

Low

1086469

KCNH2
Voltage-gated inwardly rectifying potassium channel KCNH2

1

0

High-throughput

0.279

Low

1244729

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

1244734

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.279

Low

1244742

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1244748

MAN1
Inner nuclear membrane protein Man1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025