HitPredict

Interactor 1: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Interactor 2: SH2D3 (Q8N5H7)
SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1)
Gene: SH2D3C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 860
+	Hs
		557324 RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Hs
		463048 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		YES_HUMAN (81-392): 1.72e-61: 219: 11.82
+	Hs
		557200 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Hs
		463038 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		YES_HUMAN (81-392): 1.72e-61: 219: 11.82
+	Hs
		855576 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		CRK_HUMAN (213-480): 7.42e-53: 188: 17.75
+	Hs
		855845 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		CRKL_HUMAN (220-480): 2.28e-50: 181: 18.12
+	Hs
		855701 RAB2B_HUMAN (7-215): 1.34e-83: 249: 46.98		CRK_HUMAN (213-480): 7.42e-53: 188: 17.75
+	Hs
		711290 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		SHC1_HUMAN (97-322): 5.56e-44: 170: 24.02
+	Hs
		463042 RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56		YES_HUMAN (81-392): 1.72e-61: 219: 11.82
+	Hs
		557196 RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Hs
		463431 RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56		LYN_HUMAN (127-400): 2.38e-54: 198: 11.60
+	Hs
		987666 RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		619021 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		PLCG1_HUMAN (105-427): 2.24e-26: 118: 14.37
+	Hs
		976190 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		699675 RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56		P85A_HUMAN (193-323): 4.95e-18: 91.2: 21.17