HitPredict

Interactor 1: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Interactor 2: LPP (Q93052)
Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma)
Gene: LPP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0001725 - stress fiber GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 612
+	Hs
		1156180 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		AJUBA_HUMAN (94-604): 1.26e-58: 207: 26.71
+	Hs
		66048 TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82		WTIP_HUMAN (244-603): 3.8e-65: 221: 32.88
+	Hs
		878469 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		1394171 LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80		AJUBA_HUMAN (94-604): 1.26e-58: 207: 26.71
+	Hs
		878576 LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		878467 TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		1156179 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		PDLI5_HUMAN (87-612): 9.43e-35: 140: 13.18
+	Hs
		1151516 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		TRIP6_HUMAN (1-527): 1.21e-18: 91.2: 21.52
+	Hs
		1156239 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		LIMD1_HUMAN (2-535): 3.81e-18: 90.5: 15.72
+	Hs
		1151679 LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80		TRIP6_HUMAN (1-527): 1.21e-18: 91.2: 21.52
+	Hs
		1459608 LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80		LIMD1_HUMAN (2-535): 3.81e-18: 90.5: 15.72
+	Hs
		1151512 TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82		TRIP6_HUMAN (1-527): 1.21e-18: 91.2: 21.52
+	Hs
		1151602 FBLI1_HUMAN (252-572): 4.15e-67: 224: 29.61		TRIP6_HUMAN (1-527): 1.21e-18: 91.2: 21.52
+	Hs
		1116481 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		FHL3_HUMAN (440-572): 8.44e-12: 68.2: 32.35
+	Hs
		253957 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		LPXN_HUMAN (355-474): 8e-10: 63.1: 17.50
+	Hs
		1156238 ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00		TES_HUMAN (529-612): 8.29e-09: 60: 17.86
+	Hs
		1116478 TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82		FHL3_HUMAN (440-572): 8.44e-12: 68.2: 32.35
+	Hs
		253994 LIMD1_HUMAN (1-571): 5.97e-65: 226: 22.80		LPXN_HUMAN (355-474): 8e-10: 63.1: 17.50
+	Hs
		253956 TRIP6_HUMAN (63-571): 7.13e-66: 224: 32.82		LPXN_HUMAN (355-474): 8e-10: 63.1: 17.50