HitPredict

Interactor 1: M9PGI6 (M9PGI6)
Secretory 22, isoform B
Gene: Sec22

Interactor 2: Q9VU45 (Q9VU45)
LD27581p (Syntaxin 13, isoform A) (Syntaxin 13, isoform B)
Gene: Syx13

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Dm			1 284
+	Dm
		115805 M9PGI6_DROME (1-213): 2.29e-85: 253: 100.00		STX1A_DROME (21-278): 1.7e-65: 208: 15.88
+	Mm
		139056 SC22B_MOUSE (1-213): 7.33e-81: 241: 56.22		STX1A_MOUSE (43-282): 1.85e-65: 207: 18.92
+	Hs
		263248 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX1A_HUMAN (43-283): 1.5e-64: 205: 18.08
+	Hs
		263179 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX2_HUMAN (20-282): 4.37e-63: 201: 14.89
+	Hs
		263279 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX12_HUMAN (38-266): 3.19e-55: 181: 28.16
+	Hs
		178331 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX7_HUMAN (49-280): 1.62e-51: 171: 22.36
+	Hs
		263226 SC22B_HUMAN (1-213): 7.33e-81: 241: 56.22		STX4_HUMAN (20-282): 4.15e-50: 169: 16.96
+	At
		249598 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP41_ARATH (17-279): 4.79e-59: 192: 20.58
+	Dm
		115811 M9PGI6_DROME (1-213): 2.29e-85: 253: 100.00		Q7K0X9_DROME (46-280): 3.55e-44: 152: 22.31
+	At
		1352876 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP43_ARATH (17-279): 3.86e-58: 190: 18.48
+	At
		1352985 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP42_ARATH (16-279): 2.01e-56: 186: 19.64
+	At
		812702 VA722_ARATH (34-200): 8.86e-71: 216: 22.22		SY121_ARATH (13-261): 5.49e-54: 180: 18.41
+	At
		1378372 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SY121_ARATH (13-261): 5.49e-54: 180: 18.41
+	At
		955702 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SYP22_ARATH (30-267): 2.28e-52: 173: 23.02
+	At
		955681 VA713_ARATH (33-213): 2.67e-65: 202: 23.91		SYP22_ARATH (30-267): 2.28e-52: 173: 23.02
+	At
		812689 VA722_ARATH (34-200): 8.86e-71: 216: 22.22		SY111_ARATH (22-261): 1.43e-45: 157: 14.87
+	At
		1114744 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SY111_ARATH (22-261): 1.43e-45: 157: 14.87
+	At
		1352937 VA721_ARATH (34-200): 5.49e-70: 214: 21.64		SY122_ARATH (57-262): 1.44e-42: 150: 17.92
+	Sc
		605845 SEC22_YEAST (1-213): 4.77e-63: 196: 29.17		SSO2_YEAST (11-273): 8e-45: 155: 16.13
+	Sc
		605828 SEC22_YEAST (1-213): 4.77e-63: 196: 29.17		PEP12_YEAST (45-258): 8.66e-33: 123: 18.93