HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 24981860, 33961781, 37689310, 12493763, 35271311, 40437099, 20388487, 9885572, 21258344, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 425
Hs

1 488
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+ At
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+ Dm
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+ Dm
+ Dm
+ Ce
+ Hs
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+ At
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Last updated: 11Aug2025