Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 9651585, 33961781, 37689310, 40437099, 11784859, 24981860, 12453419, unassigned3799
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~Sin3a_C, Sin3a_C~WD40
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 425
Hs

1 1273
+ Hs
+ Hs
+ Hs
+ Sp
+ At
+ At
+ Dm
+ At
+ At

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Last updated: 11Aug2025