Interactor 1: CAF1 (Q24572)
Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55)
Gene: Caf1-55

Interactor 2: Q5U0Y0 (Q5U0Y0)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: Sin3A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 20566628
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~Sin3a_C, Sin3a_C~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0007346 - regulation of mitotic cell cycle
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 430
Dm

1 2062
+ Sp
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025