Protein: Q5U0Y0
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)

Gene: Q5U0Y0, Sin3A
Organism: Drosophila melanogaster
Interactions: 49
UniProt ID: Q5U0Y0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1216737

HDAC1
Histone deacetylase HDAC1

6

20

Small-scale

0.920

High

1216745

KDM5
Lysine-specific demethylase 5

3

2

Small-scale

0.827

High

1216752

Q9VWG2
FI07430p

3

10

Small-scale

0.817

High

1216755

Q9VYI2
BRMS1 transcriptional repressor

3

10

Small-scale

0.817

High

1216760

Q9W410
PHD finger protein 12

2

20

Small-scale

0.754

High

1216742

Q9VEF5
Inhibitor of growth protein

2

9

Small-scale

0.737

High

1175591

CAF1
Chromatin assembly factor 1 p55 subunit

1

11

Small-scale

0.618

High

85018

B7Z143
Protein interacting with Ttk69 and Sin3A, isoform D

2

2

Small-scale

0.586

High

1216747

Q9VQ58
BRCA2-interacting transcriptional repressor EMSY

2

3

Small-scale

0.584

High

1216753

Q9VWP5
Hat-trick, isoform D

2

11

Small-scale

0.571

High

1216733

Q86NK9
Protein deacetylase HDAC6

1

20

Small-scale

0.553

High

356647

PLK4
Serine/threonine-protein kinase PLK4

1

6

High-throughput

0.541

High

1216750

Q9VUB5
UpSET, isoform A

1

8

Small-scale

0.536

High

478799

BCD
Homeotic protein bicoid

1

1

Small-scale

0.501

High

86670

B9ZW35
Pyramus

1

0

High-throughput

0.486

High

120879

M9PEE1
Smallminded, isoform H

1

2

High-throughput

0.481

High

121926

M9PGZ8
Smrter, isoform G

1

6

Small-scale

0.481

High

54261

A1Z8F4
Schnurri, isoform D

1

1

Small-scale

0.479

High

701286

SUH
Suppressor of hairless protein

1

3

High-throughput

0.479

High

1173899

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

19

Small-scale

0.479

High

1216735

Q8IQI0
Sin3A-associated protein 130, isoform C

1

13

Small-scale

0.479

High

1216739

ASF1
Histone chaperone asf1

1

1

High-throughput

0.479

High

1216740

HCF
Host cell factor

1

5

Small-scale

0.479

High

1216758

Q9W1G7
LD21576p

1

3

High-throughput

0.479

High

1216762

X2JDM5
Max-binding protein MNT

1

12

Small-scale

0.479

High

145780

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

4

High-throughput

0.464

High

362500

SRC64
Tyrosine-protein kinase Src64B

1

9

High-throughput

0.464

High

386979

ACT2
Actin-42A

1

4

High-throughput

0.464

High

1216759

Q9W2X5
DUF4766 domain-containing protein

1

6

High-throughput

0.464

High

1216749

Q9VS62
Smallminded, isoform A

1

2

High-throughput

0.457

High

1216751

ELL
RNA polymerase II elongation factor Ell

1

9

High-throughput

0.457

High

1216756

Q9VYL7
Protein interacting with Ttk69 and Sin3A, isoform C

1

2

High-throughput

0.457

High

1216761

Q9XZ09
Sin3A-associated protein 130, isoform A

1

11

High-throughput

0.445

High

121221

ALDR
Aldo-keto reductase 1B

1

1

High-throughput

0.417

High

52088

A1Z6M0
Brahma associated protein 170kD

1

9

Small-scale

0.407

High

1216743

Q9VGN4
Sarcomere length short, isoform B

1

7

High-throughput

0.407

High

1216738

Q95RS0
LD10926p

1

0

High-throughput

0.365

High

234840

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

356093

DYL2
Dynein light chain 2, cytoplasmic

1

0

High-throughput

0.265

Low

1216736

RNK
Ribonuclease kappa

1

0

High-throughput

0.265

Low

1216741

Q9V9M7
Large ribosomal subunit protein eL21

1

0

High-throughput

0.265

Low

1216744

Q9VME1
FI01864p

1

0

High-throughput

0.265

Low

1216746

Q9VN21
LD30155p

1

0

High-throughput

0.265

Low

1216748

Q9VRT6
RE27477p

1

0

High-throughput

0.265

Low

1216754

DENR
Density-regulated protein homolog

1

0

High-throughput

0.265

Low

1216757

Q9W0H1
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1216732

Q7KTH6
Uncharacterized protein

1

0

High-throughput

0.251

Low

1216734

Q8I0D1
GH14831p

1

0

High-throughput

0.238

Low

726339

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025