HitPredict

Interactor 1: A0A024R161 (A0A024R161)
Guanine nucleotide-binding protein subunit gamma
Gene: DNAJC25-GNG10

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 153 Hs			1 654
+	Hs
		502546 DJC25_HUMAN (1-122): 4.86e-41: 142: 91.80		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		636461 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		714049 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		714084 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		503464 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		504564 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Rn
		419270 DJB11_RAT (32-142): 4.18e-34: 124: 27.93		BIP_RAT (1-654): 0: 918: 98.47
+	Hs
		564009 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		504860 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Mm
		588735 DJB11_MOUSE (32-142): 2.71e-34: 124: 27.93		BIP_MOUSE (1-654): 0: 917: 98.62
+	Hs
		504897 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502611 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		564202 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		636490 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		Q53FC7_HUMAN (25-635): 0: 912: 62.05
+	Hs
		483774 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		HS71B_HUMAN (26-635): 0: 911: 64.11
+	Hs
		502640 DJB11_HUMAN (32-142): 2.6e-34: 124: 27.93		BIP_HUMAN (19-654): 0: 914: 100.00
+	Mm
		222719 DNJB6_MOUSE (49-147): 5.8e-35: 126: 28.85		HS71B_MOUSE (26-635): 0: 908: 63.46
+	Hs
		636469 DNJB2_HUMAN (49-148): 1.17e-35: 127: 28.04		HSP72_HUMAN (25-636): 0: 905: 64.51
+	Hs
		871728 DNJA3_HUMAN (16-140): 7.21e-35: 127: 25.58		HSP72_HUMAN (25-636): 0: 905: 64.51
+	Hs
		871807 DJB12_HUMAN (36-147): 1.85e-34: 125: 25.00		HSP72_HUMAN (25-636): 0: 905: 64.51