HitPredict

Interactor 1: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 23663784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0010494 - cytoplasmic stress granule GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1096 Hs			1 1191
+	Hs
		1136132 LARP1_HUMAN (1-1096): 0: 747: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136121 LAR1B_HUMAN (175-1093): 0: 632: 55.38		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1174856 LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1268172 LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1136139 LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136206 LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1116598 LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37		CHD7_HUMAN (491-1004): 4.82e-13: 76.2: 7.21
+	Hs
		257638 LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		257675 LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Mm
		1351630 PCLO_MOUSE (7-823): 3.71e-10: 66.7: 11.26		PCLO_MOUSE (522-1015): 6.21e-15: 82.8: 8.09
+	Dm
		113976 M9PB30_DROME (13-810): 2.01e-13: 77.5: 9.06		M9PB30_DROME (683-1171): 5.39e-11: 69.7: 12.25