Interactor 1: UFD1 (Q19584)
Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1)
Gene: ufd-1
Interactor 2: NPL42 (Q95QZ9)
Nuclear protein localization protein 4 homolog 2
Gene: npl-4.2
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.64 | 0.60 | 0.624 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11731503, 14704431, unassigned701 |
| Identification Methods | two hybrid, two hybrid pooling approach |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0009792 - embryo development ending in birth or egg hatching GO:0034098 - VCP-NPL4-UFD1 AAA ATPase complex GO:0036503 - ERAD pathway |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
