HitPredict

Interactor 1: FADA5 (I6XHI4)
Steroid 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA5) (Beta-ketoacyl-CoA thiolase)
Gene: FADA5

Interactor 2: FADA5 (I6XHI4)
Steroid 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acetyltransferase FadA5) (Beta-ketoacyl-CoA thiolase)
Gene: FADA5

Species: Mycobacterium tuberculosis H37Rv

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 25482540
Identification Methods molecular sieving, light scattering, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms GO:0003988 - acetyl-CoA C-acyltransferase activity
GO:0006635 - fatty acid beta-oxidation
GO:0006707 - cholesterol catabolic process
GO:0010124 - phenylacetate catabolic process
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 391
Mt

1 391
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ At
+ Sc
+ Ec
+ Mm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025