Interactor 1: THIM (Q8BWT1)
3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)
Gene: Acaa2

Interactor 2: THIM (Q8BWT1)
3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)
Gene: Acaa2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0003986 - acetyl-CoA hydrolase activity
GO:0003988 - acetyl-CoA C-acyltransferase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
and 7 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 397
Mm

1 397
+ Ec
+ At
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Sc
+ Mm
+ Mm
+ Sc
+ Mt

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Last updated: 11Aug2025