HitPredict - High confidence protein-protein interactions

Interactor 1: THIL (P24752)
Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2)
Gene: ACAT1

Interactor 2: THIL (P24752)
Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (T2)
Gene: ACAT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Interacting Pfam domains	Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms	GO:0001889 - liver development GO:0003985 - acetyl-CoA C-acetyltransferase activity GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0005783 - endoplasmic reticulum and 19 others more... GO:0006085 - acetyl-CoA biosynthetic process GO:0006550 - L-isoleucine catabolic process GO:0006635 - fatty acid beta-oxidation GO:0009725 - response to hormone GO:0015936 - coenzyme A metabolic process GO:0015937 - coenzyme A biosynthetic process GO:0016453 - C-acetyltransferase activity GO:0019899 - enzyme binding GO:0030955 - potassium ion binding GO:0034736 - cholesterol O-acyltransferase activity GO:0042594 - response to starvation GO:0046356 - acetyl-CoA catabolic process GO:0046952 - ketone body catabolic process GO:0060612 - adipose tissue development GO:0070062 - extracellular exosome GO:0072229 - metanephric proximal convoluted tubule development GO:0120225 - coenzyme A binding GO:1902224 - ketone body metabolic process GO:1902860 - propionyl-CoA biosynthetic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1	427
Hs

1	427

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Last updated: 11Aug2025