HitPredict

Interactor 1: CE128 (Q6ZU80)
Centrosomal protein of 128 kDa (Cep128)
Gene: CEP128

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0008104 - protein localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1094 Hs			1 1088
+	Hs
		149340 CTRO_HUMAN (8-579): 1.39e-14: 81.1: 11.50		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325611 MYH6_HUMAN (3-795): 2.32e-31: 136: 12.35		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325612 MYH8_HUMAN (2-703): 1.14e-26: 120: 12.98		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325605 MYH3_HUMAN (443-1093): 7.42e-23: 108: 11.76		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325609 MYH7_HUMAN (2-612): 1.16e-22: 107: 12.52		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325936 MYH13_HUMAN (1-396): 6.51e-11: 69: 9.90		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		568711 CE128_HUMAN (1-1094): 2.14e-74: 269: 100.00		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		528359 MYH6_HUMAN (3-795): 2.32e-31: 136: 12.35		KAPCB_HUMAN (638-1022): 1.92e-133: 410: 31.36
+	Mm
		554901 MYH6_MOUSE (364-1091): 9.29e-30: 130: 13.19		KPCE_MOUSE (554-1010): 2.84e-130: 415: 29.92
+	Mm
		554927 MYH7_MOUSE (2-612): 1.29e-22: 107: 12.52		KPCE_MOUSE (554-1010): 2.84e-130: 415: 29.92
+	Hs
		725079 MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		681696 MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		568568 MYH10_HUMAN (662-1091): 3.2e-16: 86.4: 11.32		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		724784 MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20		KPCE_HUMAN (554-1010): 1.06e-129: 413: 29.92
+	Hs
		568567 MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		1268126 MY18A_HUMAN (271-1014): 3.68e-28: 125: 13.96		MRCKB_HUMAN (658-1007): 1.11e-70: 261: 40.34
+	Hs
		254459 ROCK2_HUMAN (187-807): 2.23e-12: 73.9: 23.21		KS6A3_HUMAN (519-990): 8.69e-81: 281: 19.63
+	Hs
		254476 ROCK2_HUMAN (187-807): 2.23e-12: 73.9: 23.21		ROCK1_HUMAN (640-1008): 1.28e-70: 260: 38.77
+	Hs
		724810 MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20		ROCK1_HUMAN (640-1008): 1.28e-70: 260: 38.77
+	Bt
		1100183 ROCK2_BOVIN (187-807): 2.22e-11: 70.5: 23.07		ROCK2_BOVIN (640-1008): 6.44e-67: 248: 37.17