HitPredict

Interactor 1: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030027 - lamellipodium
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1250 Hs			1 508
+	Hs
		1173971 RAPH1_HUMAN (1-1250): 0: 627: 100.00		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		1031685 GRB10_HUMAN (111-591): 4.23e-121: 389: 24.95		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Ce
		711888 MIG10_CAEEL (190-655): 8.61e-87: 301: 32.21		Q10929_CAEEL (3-503): 2.93e-67: 225: 28.94
+	Mm
		761854 ZO1_MOUSE (514-1213): 1.47e-26: 120: 12.73		SRC8_MOUSE (291-502): 1.17e-33: 136: 20.64
+	Mm
		1351630 PCLO_MOUSE (489-1249): 2.12e-13: 77.6: 10.18		PCLO_MOUSE (91-454): 1.32e-28: 122: 15.39
+	Dm
		113976 M9PB30_DROME (498-1249): 9.58e-25: 114: 10.32		M9PB30_DROME (120-453): 4.72e-09: 61.6: 14.33
+	Hs
		257713 ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82		ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98