HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22334663
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 427
+	Hs
		935050 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		DDB2_HUMAN (1-427): 1.81e-95: 294: 100.00
+	Hs
		934971 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		DAW1_HUMAN (103-427): 2.42e-85: 268: 18.04
+	Hs
		935250 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		1174659 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		952632 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		1136695 H37_HUMAN (1-136): 3.26e-59: 181: 97.06		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		903117 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		903260 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		903128 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		792992 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		LIS1_HUMAN (5-231): 5.78e-48: 170: 12.20
+	Hs
		935208 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		TBL1R_HUMAN (233-427): 3.6e-24: 106: 17.48
+	Hs
		934796 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		TAF5_HUMAN (153-330): 4.83e-21: 97.9: 23.46
+	Hs
		1074789 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		TAF5_HUMAN (153-330): 4.83e-21: 97.9: 23.46
+	Sc
		902161 H3_YEAST (1-136): 7.77e-56: 172: 88.97		CMR1_YEAST (98-427): 4.9e-26: 112: 17.49
+	Hs
		952358 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		TAF5_HUMAN (153-330): 4.83e-21: 97.9: 23.46
+	Hs
		921521 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		245614 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		TBL1X_HUMAN (277-427): 5.26e-19: 91: 11.25
+	Hs
		196999 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		PRP4_HUMAN (273-421): 2.01e-16: 83.2: 12.67
+	Sc
		742936 H3_YEAST (1-136): 7.77e-56: 172: 88.97		GBLP_YEAST (123-315): 1.38e-10: 64: 16.34
+	Sc
		730779 CENPA_YEAST (18-134): 1.58e-41: 139: 56.67		GBLP_YEAST (123-315): 1.38e-10: 64: 16.34