HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: ASF1A (Q9Y294)
Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)
Gene: ASF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	26167883
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 204
+	Hs
		935389 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Mm
		935461 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Hs
		1086358 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Mm
		952267 H32_MOUSE (1-136): 3.73e-61: 186: 100.00		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Gg
		952273 H32_CHICK (1-136): 3.73e-61: 186: 100.00		ASF1_CHICK (1-204): 2.31e-128: 361: 100.00
+	Hs
		952711 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Mm
		952765 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Gg
		952779 H33_CHICK (1-136): 1.59e-61: 186: 97.06		ASF1_CHICK (1-204): 2.31e-128: 361: 100.00
+	Hs
		935298 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Hs
		1086330 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Hs
		952660 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Mm
		935463 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Mm
		952269 H32_MOUSE (1-136): 3.73e-61: 186: 100.00		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Mm
		952769 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Hs
		828399 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Dm
		356097 H3_DROME (1-136): 3.73e-61: 186: 100.00		ASF1_DROME (1-203): 1.05e-97: 284: 56.88
+	Sp
		251626 H31_SCHPO (1-136): 2.22e-59: 181: 91.91		ASF1_SCHPO (1-169): 1.83e-84: 252: 51.43
+	Sc
		689932 H3_YEAST (1-136): 7.77e-56: 172: 88.97		ASF1_YEAST (1-168): 7.8e-88: 261: 54.76