HitPredict

Interactor 1: Q7K2L1 (Q7K2L1)
Origin recognition complex subunit 3
Gene: Orc3

Interactor 2: Q9VSM9 (Q9VSM9)
Cell division control protein
Gene: Cdc6

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	32848132, 29899147
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003688 - DNA replication origin binding GO:0005634 - nucleus GO:0006270 - DNA replication initiation
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 721 Dm			1 662
+	Dm
		184168 Q7K2L1_DROME (1-721): 0: 873: 100.00		ORC1_DROME (12-650): 1.39e-114: 367: 20.64
+	Hs
		1306117 ORC3_HUMAN (4-721): 0: 721: 32.27		CDC6_HUMAN (87-655): 7.11e-143: 429: 32.09
+	Hs
		1033405 ORC3_HUMAN (4-721): 0: 721: 32.27		ORC1_HUMAN (6-647): 6.11e-134: 416: 21.11
+	Dm
		1179280 Q7K2L1_DROME (1-721): 0: 873: 100.00		Q9W102_DROME (246-656): 1.09e-73: 246: 13.28
+	At
		1150653 ORC3_ARATH (19-721): 0: 606: 21.57		ORC1A_ARATH (32-651): 5.24e-150: 456: 17.73
+	Dm
		1096599 Q7K2L1_DROME (1-721): 0: 873: 100.00		ORC5_DROME (257-490): 3.42e-37: 146: 15.77
+	Hs
		217839 ORC3_HUMAN (4-721): 0: 721: 32.27		ORC4_HUMAN (230-658): 1.3e-91: 292: 14.89
+	Hs
		217282 ORC3_HUMAN (4-721): 0: 721: 32.27		ORC5_HUMAN (262-449): 1.08e-33: 135: 16.34
+	At
		1150652 ORC3_ARATH (19-721): 0: 606: 21.57		ORC4_ARATH (243-654): 4.62e-74: 246: 16.05
+	Sp
		872884 ORC3_SCHPO (56-721): 1.32e-144: 440: 19.01		ORC1_SCHPO (154-653): 3.67e-108: 344: 21.93
+	Sp
		783441 ORC3_SCHPO (56-721): 1.32e-144: 440: 19.01		CDC18_SCHPO (97-650): 2.8e-101: 322: 25.00
+	Sp
		1013457 ORC3_SCHPO (56-721): 1.32e-144: 440: 19.01		ORC4_SCHPO (20-607): 2.18e-76: 265: 12.72