Protein: CDK2
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)

Gene: CDK2
Organism: Mus musculus
Interactions: 26
UniProt ID: P97377

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000287 - magnesium ion binding
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000781 - chromosome, telomeric region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021259

CCNE1
G1/S-specific cyclin-E1

13

20

Small-scale

0.979

High

813541

CDN1A
Cyclin-dependent kinase inhibitor 1

9

20

Small-scale

0.962

High

908677

CCNA2
Cyclin-A2

7

20

Small-scale

0.954

High

857019

CDN1B
Cyclin-dependent kinase inhibitor 1B

5

20

Small-scale

0.909

High

1021258

CCNA1
Cyclin-A1

4

20

Small-scale

0.885

High

847012

H11
Histone H1.1

7

20

Small-scale

0.744

High

671888

CCND1
G1/S-specific cyclin-D1

2

20

Small-scale

0.737

High

586400

H12
Histone H1.2

3

20

Small-scale

0.655

High

921235

CEBPA
CCAAT/enhancer-binding protein alpha

2

5

Small-scale

0.624

High

700344

BRAF
Serine/threonine-protein kinase B-raf

1

18

High-throughput

0.618

High

718862

CCND2
G1/S-specific cyclin-D2

1

20

Small-scale

0.618

High

1021261

CCNC
Cyclin-C

1

20

Small-scale

0.618

High

561636

RB
Retinoblastoma-associated protein

2

11

Small-scale

0.602

High

382469

P53
Cellular tumor antigen p53

1

6

Small-scale

0.501

High

522162

BCL2
Apoptosis regulator Bcl-2

1

5

Small-scale

0.501

High

534014

H10
Histone H1.0

1

8

Small-scale

0.501

High

847025

H15
Histone H1.5

1

20

Small-scale

0.501

High

1021257

BRCA2
Breast cancer type 2 susceptibility protein homolog

1

1

Small-scale

0.501

High

1021260

NPM
Nucleophosmin

1

3

Small-scale

0.501

High

313308

CDC6
Cell division control protein 6 homolog

1

14

Small-scale

0.479

High

609535

PCNA
Proliferating cell nuclear antigen

1

6

Small-scale

0.479

High

866484

PA24A
Cytosolic phospholipase A2

1

1

Small-scale

0.479

High

927724

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

989681

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

13

High-throughput

0.479

High

1021262

DPPA3
Developmental pluripotency-associated protein 3

1

1

Small-scale

0.479

High

832467

TNFC
Lymphotoxin-beta

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025