Interactor 1: NOS1 (P29475)
Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)
Gene: NOS1

Interactor 2: SNTA1 (Q13424)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)
Gene: SNTA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 9412493, 33961781
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ
Common GO terms GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0006936 - muscle contraction
GO:0017080 - sodium channel regulator activity
and 3 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1434
Hs

1 505
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024