HitPredict

Interactor 1: SNP23 (O00161)
Synaptosomal-associated protein 23 (SNAP-23) (Vesicle-membrane fusion protein SNAP-23)
Gene: SNAP23

Interactor 2: STX7 (O15400)
Syntaxin-7
Gene: STX7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	26186194, 28514442, 34079125, 33961781, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0019905 - syntaxin binding GO:0031201 - SNARE complex GO:0042582 - azurophil granule and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 261
+	Hs
		117977 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX2_HUMAN (7-256): 2.04e-65: 207: 27.13
+	Hs
		118037 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1A_HUMAN (6-259): 6.04e-65: 205: 24.05
+	Hs
		118010 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX1B_HUMAN (7-258): 2.12e-64: 204: 22.31
+	Mm
		140165 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX1A_MOUSE (7-259): 3.19e-65: 206: 24.90
+	Rn
		250768 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX1B_RAT (7-258): 2.12e-64: 204: 22.31
+	Hs
		118048 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX12_HUMAN (10-244): 3.42e-58: 188: 54.01
+	Dm
		1098103 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		STX1A_DROME (1-256): 1.06e-63: 202: 22.73
+	Hs
		118028 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX3_HUMAN (4-237): 2.81e-52: 173: 23.33
+	Ce
		183449 O62414_CAEEL (4-209): 2.49e-58: 184: 46.60		STX1A_CAEEL (2-259): 8.94e-65: 205: 22.02
+	Hs
		118025 SNP23_HUMAN (1-211): 1.06e-71: 218: 100.00		STX4_HUMAN (5-256): 7.24e-50: 167: 23.85
+	Dm
		739422 SNP25_DROME (6-210): 1.87e-57: 182: 50.24		STX1A_DROME (1-256): 1.06e-63: 202: 22.73
+	Rn
		250771 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX3_RAT (4-237): 4.92e-51: 170: 23.75
+	Mm
		140169 SNP23_MOUSE (1-211): 2.55e-68: 209: 87.20		STX3_MOUSE (4-237): 6.73e-51: 169: 23.75
+	Rn
		250772 SNP23_RAT (1-211): 6.18e-69: 211: 87.20		STX4_RAT (5-256): 4.87e-49: 165: 24.23
+	At
		1351792 SNP33_ARATH (1-210): 2.42e-60: 192: 22.54		SY121_ARATH (7-239): 7.67e-52: 174: 18.15
+	Dm
		1178788 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q7K0X9_DROME (10-256): 4.5e-44: 152: 38.85
+	Dm
		1366725 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VU45_DROME (10-260): 1.85e-43: 150: 23.41
+	Dm
		739424 SNP25_DROME (6-210): 1.87e-57: 182: 50.24		Q7K0X9_DROME (10-256): 4.5e-44: 152: 38.85
+	Dm
		1366722 Q9VH76_DROME (6-211): 4.47e-61: 191: 47.57		Q9VR90_DROME (149-246): 5.68e-13: 69.7: 41.84
+	Dm
		739433 SNP25_DROME (6-210): 1.87e-57: 182: 50.24		Q9VR90_DROME (149-246): 5.68e-13: 69.7: 41.84