HitPredict

Interactor 1: STX4 (Q7KVY7)
Syntaxin-4
Gene: Syx4

Interactor 2: Q9VH76 (Q9VH76)
Synaptosomal-associated protein
Gene: Snap24

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex GO:0061025 - membrane fusion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 333 Dm			1 212
+	Dm
		1098103 STX1A_DROME (59-325): 2.18e-71: 224: 21.90		Q9VH76_DROME (1-212): 4.78e-71: 216: 100.00
+	Ce
		183449 STX1A_CAEEL (53-332): 3.73e-75: 234: 21.68		O62414_CAEEL (6-210): 6.59e-62: 193: 54.11
+	Hs
		118010 STX1B_HUMAN (59-330): 3.65e-74: 232: 20.79		SNP23_HUMAN (14-212): 1.21e-61: 192: 47.81
+	Hs
		117977 STX2_HUMAN (59-330): 1.28e-73: 230: 19.71		SNP23_HUMAN (14-212): 1.21e-61: 192: 47.81
+	Rn
		250768 STX1B_RAT (59-330): 3.65e-74: 232: 20.79		SNP23_RAT (14-212): 1.41e-59: 187: 51.71
+	Hs
		893263 STX1B_HUMAN (59-330): 3.65e-74: 232: 20.79		SNP25_HUMAN (5-212): 2.01e-59: 187: 58.65
+	Rn
		893305 STX1B_RAT (59-330): 3.65e-74: 232: 20.79		SNP25_RAT (5-212): 2.01e-59: 187: 58.65
+	Hs
		699251 STX2_HUMAN (59-330): 1.28e-73: 230: 19.71		SNP25_HUMAN (5-212): 2.01e-59: 187: 58.65
+	Hs
		118037 STX1A_HUMAN (82-327): 2.03e-71: 224: 23.72		SNP23_HUMAN (14-212): 1.21e-61: 192: 47.81
+	Hs
		320293 STX1B_HUMAN (59-330): 3.65e-74: 232: 20.79		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Mm
		192844 STX1A_MOUSE (57-330): 1.4e-72: 228: 21.71		SNP25_MOUSE (5-212): 2.01e-59: 187: 58.65
+	Mm
		140165 STX1A_MOUSE (57-330): 1.4e-72: 228: 21.71		SNP23_MOUSE (14-212): 5.62e-59: 186: 51.22
+	Hs
		320269 STX2_HUMAN (59-330): 1.28e-73: 230: 19.71		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Rn
		699172 STX1A_RAT (57-330): 2.38e-72: 227: 21.71		SNP25_RAT (5-212): 2.01e-59: 187: 58.65
+	Bt
		699168 STX1A_BOVIN (57-327): 4.18e-72: 226: 21.22		SNP25_BOVIN (5-212): 2.01e-59: 187: 58.65
+	Dm
		739422 STX1A_DROME (59-325): 2.18e-71: 224: 21.90		SNP25_DROME (9-211): 5.69e-60: 188: 71.92
+	Mm
		192859 STX1A_MOUSE (57-330): 1.4e-72: 228: 21.71		SNP29_MOUSE (7-209): 3.03e-57: 183: 21.33
+	Hs
		893278 STX1A_HUMAN (82-327): 2.03e-71: 224: 23.72		SNP25_HUMAN (5-212): 2.01e-59: 187: 58.65
+	Hs
		320326 STX1A_HUMAN (82-327): 2.03e-71: 224: 23.72		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Dm
		1098113 STX1A_DROME (59-325): 2.18e-71: 224: 21.90		Q9W1I8_DROME (7-211): 4.67e-49: 163: 24.00