HitPredict

Interactor 1: SNP29 (O95721)
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
Gene: SNAP29

Interactor 2: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex GO:0031629 - synaptic vesicle fusion to presynaptic active zone membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 288
+	Hs
		320293 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX1B_HUMAN (1-287): 6.03e-81: 247: 64.81
+	Mm
		192859 SNP29_MOUSE (1-258): 2.07e-81: 246: 83.08		STX1A_MOUSE (1-287): 5.2e-78: 240: 65.63
+	Hs
		320326 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46
+	Hs
		320309 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Hs
		320316 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX3_HUMAN (1-287): 6.25e-60: 194: 63.79
+	Hs
		320453 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		X5D7S1_HUMAN (1-285): 2.49e-59: 191: 55.59
+	Hs
		117977 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX2_HUMAN (1-288): 5.69e-82: 250: 100.00
+	Hs
		118010 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX1B_HUMAN (1-287): 6.03e-81: 247: 64.81
+	Hs
		118037 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46
+	Hs
		269383 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX11_HUMAN (1-273): 1.04e-51: 172: 31.82
+	Hs
		152124 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX16_HUMAN (3-263): 1.59e-50: 171: 19.55
+	Hs
		178350 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX7_HUMAN (36-284): 1.29e-48: 164: 27.78
+	Hs
		320349 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		STX12_HUMAN (26-270): 4.71e-48: 162: 25.00
+	Hs
		320390 SNP29_HUMAN (1-258): 4.55e-83: 250: 100.00		TSNA1_HUMAN (25-288): 2.21e-45: 161: 18.96
+	Hs
		118025 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Hs
		118028 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX3_HUMAN (1-287): 6.25e-60: 194: 63.79
+	Hs
		117936 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX11_HUMAN (1-273): 1.04e-51: 172: 31.82
+	Hs
		66335 A8K287_HUMAN (41-258): 1.14e-58: 187: 20.18		STX11_HUMAN (1-273): 1.04e-51: 172: 31.82
+	Hs
		117929 SNP23_HUMAN (41-258): 1.14e-58: 187: 20.18		STX7_HUMAN (36-284): 1.29e-48: 164: 27.78
+	At
		1114738 SNP29_ARATH (1-258): 2.53e-60: 192: 21.85		SY111_ARATH (4-265): 1.41e-44: 155: 21.69