Protein: STA5B
Signal transducer and activator of transcription 5B

Gene: STA5B, STAT5B
Organism: Homo sapiens
Interactions: 98
UniProt ID: P51692

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838347

STA5A
Signal transducer and activator of transcription 5A

5

16

Small-scale

0.922

High

907258

STA5B
Signal transducer and activator of transcription 5B

4

16

Small-scale

0.896

High

253328

JAK2
Tyrosine-protein kinase JAK2

3

20

Small-scale

0.835

High

362999

EGFR
Epidermal growth factor receptor

3

20

Small-scale

0.827

High

907284

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.783

High

907289

STAC
SH3 and cysteine-rich domain-containing protein

2

5

High-throughput

0.783

High

532064

KIT
Mast/stem cell growth factor receptor Kit

2

13

Small-scale

0.768

High

439687

INSR
Insulin receptor

2

14

Small-scale

0.743

High

611044

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

17

Small-scale

0.724

High

658662

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.713

High

362218

ABL1
Tyrosine-protein kinase ABL1

1

15

Small-scale

0.710

High

907265

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

17

Small-scale

0.692

High

155092

SOCS2
Suppressor of cytokine signaling 2

1

20

High-throughput

0.665

High

533838

GHR
Growth hormone receptor

1

20

Small-scale

0.647

High

907259

JAK3
Tyrosine-protein kinase JAK3

1

20

Small-scale

0.621

High

411612

NTRK1
High affinity nerve growth factor receptor

1

19

High-throughput

0.618

High

641140

FGFR2
Fibroblast growth factor receptor 2

1

19

Small-scale

0.618

High

711069

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

12

Small-scale

0.618

High

711282

SHC1
SHC-transforming protein 1

1

10

Small-scale

0.618

High

714595

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

Small-scale

0.618

High

827710

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.618

High

838027

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.618

High

855838

CRKL
Crk-like protein

1

4

Small-scale

0.618

High

907271

PTK6
Protein-tyrosine kinase 6

1

13

Small-scale

0.618

High

907274

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.618

High

907279

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.618

High

907292

CISH
Cytokine-inducible SH2-containing protein

1

20

Small-scale

0.618

High

907264

RT06
Small ribosomal subunit protein bS6m

3

1

High-throughput

0.607

High

288377

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

6

High-throughput

0.606

High

807991

CDN1A
Cyclin-dependent kinase inhibitor 1

2

1

High-throughput

0.606

High

907262

LMO4
LIM domain transcription factor LMO4

2

3

High-throughput

0.606

High

907267

RBBP4
Histone-binding protein RBBP4

2

1

High-throughput

0.606

High

907268

CAF1A
Chromatin assembly factor 1 subunit A

2

1

High-throughput

0.606

High

575819

IL2RB
Interleukin-2 receptor subunit beta

2

20

Small-scale

0.602

High

619625

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.601

High

907260

EPHA4
Ephrin type-A receptor 4

1

12

High-throughput

0.590

High

907269

NMI
N-myc-interactor

1

6

Small-scale

0.586

High

907280

MED25
Mediator of RNA polymerase II transcription subunit 25

2

0

High-throughput

0.580

High

907283

PPL13
Placental protein 13-like

2

0

High-throughput

0.580

High

907266

DDR1
Epithelial discoidin domain-containing receptor 1

1

19

Small-scale

0.575

High

132836

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

3

High-throughput

0.536

High

470936

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

539145

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.536

High

586255

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.536

High

592817

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.518

High

829035

IL15
Interleukin-15

1

0

High-throughput

0.518

High

664691

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.515

High

906988

CCR5
C-C chemokine receptor type 5

1

6

Small-scale

0.515

High

907295

STAP2
Signal-transducing adaptor protein 2

1

1

Small-scale

0.515

High

116820

I6L957
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.515

High

907281

ZN410
Zinc finger protein 410

1

2

High-throughput

0.515

High

249591

SNX3
Sorting nexin-3

1

0

High-throughput

0.513

High

484444

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

884619

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

907273

MVP
Major vault protein

1

0

High-throughput

0.513

High

907291

PUS7L
Pseudouridylate synthase PUS7L

1

0

High-throughput

0.513

High

907293

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.513

High

907294

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.513

High

421753

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

907277

ELP2
Elongator complex protein 2

1

5

Small-scale

0.501

High

447715

TPM3
Tropomyosin alpha-3 chain

1

4

High-throughput

0.500

High

482862

TPM1
Tropomyosin alpha-1 chain

1

3

High-throughput

0.500

High

552539

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.500

High

610270

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.500

High

767744

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.500

High

907261

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.500

High

907263

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.500

High

907270

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.500

High

907275

DREB
Drebrin

1

1

High-throughput

0.500

High

522401

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.489

High

124279

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.481

High

650652

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.481

High

176042

KDM6B
Lysine-specific demethylase 6B

1

1

Small-scale

0.479

High

241144

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

378616

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.479

High

403925

GCR
Glucocorticoid receptor

1

19

Small-scale

0.479

High

442900

PRGR
Progesterone receptor

1

17

Small-scale

0.479

High

533904

IRF1
Interferon regulatory factor 1

1

20

Small-scale

0.479

High

576192

PO2F1
POU domain, class 2, transcription factor 1

1

5

Small-scale

0.479

High

588250

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

596943

PRLR
Prolactin receptor

1

20

Small-scale

0.479

High

606459

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

635837

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

1

Small-scale

0.479

High

907287

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

Small-scale

0.479

High

907298

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.479

High

907276

DMRTA
Doublesex- and mab-3-related transcription factor A1

1

0

High-throughput

0.460

High

907278

AFTIN
Aftiphilin

1

0

High-throughput

0.460

High

907285

TFG
Protein TFG

1

0

High-throughput

0.460

High

907297

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.460

High

907296

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

299119

FLOT1
Flotillin-1

1

5

High-throughput

0.457

High

907272

FLOT2
Flotillin-2

1

5

High-throughput

0.457

High

907286

CBP
CREB-binding protein

1

14

Small-scale

0.445

High

907282

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

0

High-throughput

0.328

High

907290

TRMO
tRNA

2

0

High-throughput

0.328

High

907122

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

907288

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025