HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26598620
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 310
+	Hs
		436250 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		436602 RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		940529 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		1296780 RHOV_HUMAN (49-258): 3.82e-87: 260: 60.66		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		940472 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		1183635 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		892311 RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		940394 RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		925182 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		1166654 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		LRIG3_HUMAN (26-241): 1.3e-32: 129: 17.97
+	Hs
		925776 RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		913999 RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		900368 RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		545313 RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		914506 RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		901110 RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		893890 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		1031144 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		PTK7_HUMAN (31-231): 1.47e-23: 103: 16.51
+	Hs
		1183491 RHOU_HUMAN (1-258): 1.4e-83: 252: 100.00		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69
+	Hs
		914253 RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87		TITIN_HUMAN (44-243): 7.16e-09: 59.1: 12.21