HitPredict

Interactor 1: INAVA (Q3KP66)
Innate immunity activator protein
Gene: INAVA

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	29420262, 28514442, 30355448, 33961781, 31022698, unassigned3799
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 663 Hs			1 400
+	Hs
		1149050 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH1_HUMAN (2-397): 7.69e-176: 497: 83.08
+	Hs
		1186194 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH4_HUMAN (1-395): 3.29e-169: 480: 68.61
+	Hs
		225482 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH3_HUMAN (22-395): 5.55e-167: 474: 82.89
+	Hs
		1149069 FRM4B_HUMAN (85-373): 1.08e-106: 348: 31.89		CYH1_HUMAN (2-397): 7.69e-176: 497: 83.08
+	Mm
		148525 FRM4B_MOUSE (85-373): 3.85e-104: 341: 29.47		CYH3_MOUSE (22-395): 7.24e-165: 469: 82.09
+	Hs
		1149067 FRM4A_HUMAN (112-397): 2.84e-92: 309: 43.05		CYH1_HUMAN (2-397): 7.69e-176: 497: 83.08
+	Hs
		1454790 FRM4A_HUMAN (112-397): 2.84e-92: 309: 43.05		CYH4_HUMAN (1-395): 3.29e-169: 480: 68.61
+	Hs
		1392978 CC120_HUMAN (110-369): 7.23e-52: 191: 26.10		CYH2_HUMAN (1-400): 3e-180: 508: 100.00
+	Hs
		1149059 CC120_HUMAN (110-369): 7.23e-52: 191: 26.10		CYH1_HUMAN (2-397): 7.69e-176: 497: 83.08
+	Hs
		1393011 CC120_HUMAN (110-369): 7.23e-52: 191: 26.10		CYH4_HUMAN (1-395): 3.29e-169: 480: 68.61
+	Hs
		225490 CC120_HUMAN (110-369): 7.23e-52: 191: 26.10		CYH3_HUMAN (22-395): 5.55e-167: 474: 82.89