HitPredict

Interactor 1: CYH3 (O43739)
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)
Gene: CYTH3

Interactor 2: INAVA (Q3KP66)
Innate immunity activator protein
Gene: INAVA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	28514442, 29420262, 30355448, 33961781, 31022698, unassigned3799
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 663
+	Hs
		1149050 CYH1_HUMAN (1-400): 1.23e-176: 499: 84.25		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1186184 CYH2_HUMAN (3-400): 1.01e-174: 494: 80.91		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1186194 CYH4_HUMAN (13-400): 4.39e-168: 477: 72.94		INAVA_HUMAN (1-663): 0: 1010: 100.00
+	Hs
		1149069 CYH1_HUMAN (1-400): 1.23e-176: 499: 84.25		FRM4B_HUMAN (85-373): 1.08e-106: 348: 31.89
+	Mm
		148525 CYH3_MOUSE (1-400): 2.91e-171: 485: 98.75		FRM4B_MOUSE (85-373): 3.85e-104: 341: 29.47
+	Hs
		1149067 CYH1_HUMAN (1-400): 1.23e-176: 499: 84.25		FRM4A_HUMAN (112-397): 2.84e-92: 309: 43.05
+	Hs
		1454790 CYH4_HUMAN (13-400): 4.39e-168: 477: 72.94		FRM4A_HUMAN (112-397): 2.84e-92: 309: 43.05
+	Hs
		1149059 CYH1_HUMAN (1-400): 1.23e-176: 499: 84.25		CC120_HUMAN (110-369): 7.23e-52: 191: 26.10
+	Hs
		1392978 CYH2_HUMAN (3-400): 1.01e-174: 494: 80.91		CC120_HUMAN (110-369): 7.23e-52: 191: 26.10
+	Hs
		225490 CYH3_HUMAN (12-400): 2.07e-172: 488: 100.00		CC120_HUMAN (110-369): 7.23e-52: 191: 26.10
+	Hs
		1393011 CYH4_HUMAN (13-400): 4.39e-168: 477: 72.94		CC120_HUMAN (110-369): 7.23e-52: 191: 26.10