Protein: CYH3
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)

Gene: CYH3, CYTH3
Organism: Homo sapiens
Interactions: 40
UniProt ID: O43739

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001726 - ruffle
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225488

CNKR1
Connector enhancer of kinase suppressor of ras 1

6

18

High-throughput

0.957

High

225486

ICEF1
Interactor protein for cytohesin exchange factors 1

5

18

Small-scale

0.930

High

225493

WDR83
WD repeat domain-containing protein 83

3

2

High-throughput

0.751

High

225482

INAVA
Innate immunity activator protein

6

11

Small-scale

0.733

High

225480

ITSN1
Intersectin-1

1

7

High-throughput

0.698

High

225479

CYH1
Cytohesin-1

1

9

High-throughput

0.691

High

225469

FOSL2
Fos-related antigen 2

4

7

High-throughput

0.691

High

225477

GPS2
G protein pathway suppressor 2

4

1

High-throughput

0.691

High

225490

CC120
Coiled-coil domain-containing protein 120

6

11

High-throughput

0.673

High

225462

CYTIP
Cytohesin-interacting protein

3

17

High-throughput

0.667

High

217016

MS18B
Protein Mis18-beta

4

0

High-throughput

0.661

High

225465

INSR
Insulin receptor

1

7

Small-scale

0.646

High

225470

IRS1
Insulin receptor substrate 1

1

6

Small-scale

0.646

High

225475

IN35
Interferon-induced 35 kDa protein

3

0

High-throughput

0.636

High

225478

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.618

High

225485

SYCE1
Synaptonemal complex central element protein 1

2

2

High-throughput

0.588

High

225474

ARFP2
Arfaptin-2

2

0

High-throughput

0.580

High

225494

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

6

High-throughput

0.541

High

225476

ANK2
Ankyrin-2

1

3

High-throughput

0.536

High

225492

ODAD1
Outer dynein arm-docking complex subunit 1

1

3

High-throughput

0.489

High

225471

SYUA
Alpha-synuclein

1

5

High-throughput

0.481

High

225472

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

Small-scale

0.481

High

225461

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

225473

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

4

Small-scale

0.479

High

225487

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

225497

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

1

1

High-throughput

0.479

High

167482

TX1B3
Tax1-binding protein 3

1

10

High-throughput

0.445

High

225466

SCHI1
Schwannomin-interacting protein 1

1

1

High-throughput

0.445

High

225468

FOSL1
Fos-related antigen 1

1

7

High-throughput

0.445

High

225483

P5CR3
Pyrroline-5-carboxylate reductase 3

1

2

High-throughput

0.445

High

225484

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.445

High

225463

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.426

High

225460

ZNRD2
Protein ZNRD2

1

2

High-throughput

0.407

High

225481

TPD53
Tumor protein D53

1

1

High-throughput

0.407

High

225489

KCD12
BTB/POZ domain-containing protein KCTD12

1

6

High-throughput

0.407

High

225495

FBLN5
Fibulin-5

1

1

High-throughput

0.407

High

225496

ATIF1
ATPase inhibitor, mitochondrial

1

1

High-throughput

0.407

High

225464

CRP

1

0

High-throughput

0.232

Low

225467

PSPC
Surfactant protein C

1

0

High-throughput

0.232

Low

225491

HIPL1
HHIP-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025