Interactor 1: HACE1 (Q3U0D9)
E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1)
Gene: HACE1
Interactor 2: OPTN (Q8K3K8)
Optineurin
Gene: OPTN
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.80 | 0.635 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25026213 |
| Identification Methods | pull down, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~CC2-LZ |
| Common GO terms | - |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
